Development and Evaluation of Sustained Release Tablet of Betahistine Hydrochloride Using Ion Exchange Resin Tulsion T344
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Development and Evaluation of Sustained Release Tablet of Betahistine Hydrochloride Using Ion Exchange Resin Tulsion T344
An attempt was made to sustain the release of Betahistine hydrochloride by complexation technique using strong cation-exchange resin, Tulsion T344. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, swelling time, ratio of drug : resin, and temperature. The resinate was evaluated for micromeritic properties and characterized using XRPD and IR. For ...
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متن کاملfeasibility of calcium alginate microcapsules of oral sustained release suspensions of propranolol hydrochloride using ion exchange resinates
an oral suspension could a suitable dosage form for the geriatric patients. the calcium alginate coated ion exchange resinate of propranolol hydrochloride were prepared using amberlite ir-120 by solvent evaporation. microcapsules of propranolol hydrochloride resinate were prepared by solvent evaporation technique,the suspensions were prepared by using deionised water as the vehicle. methyl cell...
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ژورنال
عنوان ژورنال: ISRN Pharmaceutics
سال: 2012
ISSN: 2090-6153
DOI: 10.5402/2012/438342